{"id":3920,"date":"2025-05-12T10:06:04","date_gmt":"2025-05-12T10:06:04","guid":{"rendered":"https:\/\/scientificworld.org\/?p=3920"},"modified":"2025-05-12T10:06:10","modified_gmt":"2025-05-12T10:06:10","slug":"broader-antibiotic-use-could-curb-cholera-outbreaks","status":"publish","type":"post","link":"https:\/\/scientificworld.org\/?p=3920","title":{"rendered":"Broader Antibiotic Use Could Curb Cholera Outbreaks"},"content":{"rendered":"\n<p>Researchers from the University of Utah Health propose that expanding antibiotic treatment for moderate cholera cases could slow or even stop outbreaks while reducing antibiotic resistance risks. Published in the&nbsp;<a href=\"http:\/\/dx.doi.org\/10.1007\/s11538-025-01432-2\"><em>Bulletin of Mathematical Biology<\/em><\/a>, their modeling study challenges current guidelines, which reserve antibiotics for severe cases.<\/p>\n\n\n\n<p>Current cholera management prioritizes rehydration and limits antibiotics to severe infections to prevent resistance. However, the study reveals that antibiotics shorten the infectious period, from two weeks to just a day, dramatically reducing transmission. By treating moderate cases in slower-spreading outbreaks, fewer people contract cholera overall, lowering cumulative antibiotic use and resistance risks.<\/p>\n\n\n\n<p>Key factors like population density and sanitation infrastructure influence outcomes. In high-transmission settings (e.g., crowded areas with poor sanitation), broader antibiotic use may not offset resistance concerns. But in slower-spreading scenarios, it could halt outbreaks entirely.<\/p>\n\n\n\n<p>\u201cThis might be an underused opportunity for cholera control,\u201d says senior author Dr. Lindsay Keegan. Co-author Dr. Sharia Ahmed adds, \u201cAntibiotics stop cholera release into the environment, offering population-level benefits.\u201d<\/p>\n\n\n\n<p>With cholera cases rising globally by a third last year, the findings highlight a potential tool for outbreak response. Further research is needed to refine guidelines, but the study underscores the value of data-driven policy updates for infectious disease management.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Researchers from the University of Utah Health propose that expanding antibiotic treatment for moderate cholera cases could slow or even stop outbreaks while reducing antibiotic resistance risks. Published in the&nbsp;Bulletin of Mathematical Biology, their modeling study challenges current guidelines, which reserve antibiotics for severe cases. Current cholera management prioritizes rehydration and limits antibiotics to severe [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1221],"tags":[1671,1452],"class_list":["post-3920","post","type-post","status-publish","format-standard","hentry","category-health-sciences","tag-cholera","tag-health-sciences"],"_links":{"self":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/3920","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3920"}],"version-history":[{"count":1,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/3920\/revisions"}],"predecessor-version":[{"id":3921,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/3920\/revisions\/3921"}],"wp:attachment":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3920"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3920"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3920"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}