{"id":4980,"date":"2025-07-07T10:42:23","date_gmt":"2025-07-07T10:42:23","guid":{"rendered":"https:\/\/scientificworld.org\/?p=4980"},"modified":"2025-07-07T10:42:29","modified_gmt":"2025-07-07T10:42:29","slug":"new-study-confirms-adult-brain-continues-to-form-neurons-offering-hope-for-treatments","status":"publish","type":"post","link":"https:\/\/scientificworld.org\/?p=4980","title":{"rendered":"New Study Confirms Adult Brain Continues to Form Neurons, Offering Hope for Treatments"},"content":{"rendered":"\n<p>A groundbreaking study published in&nbsp;<a href=\"http:\/\/dx.doi.org\/10.1126\/science.adu9575\"><em>Science<\/em>&nbsp;<\/a>reveals that the adult human brain continues to produce new neurons in the hippocampus, a region critical for memory and learning. Led by researchers at Karolinska Institute in Sweden, the findings resolve a long-standing debate about neurogenesis in adulthood and could pave the way for innovative treatments for neurodegenerative diseases.<\/p>\n\n\n\n<p><br>The study builds on a 2013 discovery by Jonas Fris\u00e9n\u2019s team, which first demonstrated neurogenesis in adult humans using carbon-14 dating. This new research identifies the neural progenitor cells responsible for neuron formation, confirming their presence and activity in adults aged up to 78. By combining single-nucleus RNA sequencing, flow cytometry, and machine learning, the team mapped stages of neuronal development and located these cells in the hippocampus\u2019s dentate gyrus\u2014a key area for cognitive flexibility.<\/p>\n\n\n\n<p>Notably, the neural progenitors in humans share similarities with those in mice, pigs, and monkeys, but differ in gene activity. The study also found significant individual variability, with some adults showing abundant progenitor cells and others very few.<\/p>\n\n\n\n<p><br>\u201cThis confirms ongoing neuron formation in the adult brain and deepens our understanding of brain plasticity,\u201d said Professor Jonas Fris\u00e9n, lead author. \u201cThese insights could inspire regenerative therapies for conditions like Alzheimer\u2019s or depression.\u201d<\/p>\n\n\n\n<p><br>The study not only settles a fundamental question about brain adaptability but also opens doors to potential treatments targeting neurogenesis. Future research may explore how to harness these findings to combat cognitive decline and psychiatric disorders.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A groundbreaking study published in&nbsp;Science&nbsp;reveals that the adult human brain continues to produce new neurons in the hippocampus, a region critical for memory and learning. Led by researchers at Karolinska Institute in Sweden, the findings resolve a long-standing debate about neurogenesis in adulthood and could pave the way for innovative treatments for neurodegenerative diseases. The [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1093],"tags":[726,1566,1433,1091],"class_list":["post-4980","post","type-post","status-publish","format-standard","hentry","category-neuroscience","tag-health","tag-health-medicine","tag-neuroscience","tag-public-health"],"_links":{"self":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/4980","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4980"}],"version-history":[{"count":2,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/4980\/revisions"}],"predecessor-version":[{"id":4984,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/4980\/revisions\/4984"}],"wp:attachment":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4980"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4980"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4980"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}