{"id":5185,"date":"2025-07-12T10:03:53","date_gmt":"2025-07-12T10:03:53","guid":{"rendered":"https:\/\/scientificworld.org\/?p=5185"},"modified":"2025-07-12T10:03:57","modified_gmt":"2025-07-12T10:03:57","slug":"global-study-links-covid-19-and-adenoviral-vaccines-to-rare-gbs-risk-mrna-vaccines-show-no-association","status":"publish","type":"post","link":"https:\/\/scientificworld.org\/?p=5185","title":{"rendered":"Global Study Links COVID-19 and Adenoviral Vaccines to Rare GBS Risk, mRNA Vaccines Show No Association"},"content":{"rendered":"\n<p>A multinational study analyzing data from over 230 million people has revealed that SARS-CoV-2 infection and certain adenoviral COVID-19 vaccines are associated with an increased risk of Guillain-Barr\u00e9 syndrome (GBS), a rare neurological disorder. The research, published in <a href=\"http:\/\/dx.doi.org\/10.1016\/j.vaccine.2025.127291\">Vaccine<\/a>, conducted across 20 global sites, found no such link with mRNA or inactivated vaccines, reinforcing the importance of vaccine safety monitoring and the higher risks posed by COVID-19 infection itself.<\/p>\n\n\n\n<p>The study, led by the Global Vaccine Data Network (GVDN), examined healthcare data from diverse regions, including Africa, North America, Europe, and Asia. Results showed that individuals infected with SARS-CoV-2 were three times more likely to develop GBS within six weeks of infection compared to uninfected periods. Similarly, adenoviral vector vaccines (AstraZeneca and Janssen\/Johnson &amp; Johnson) were linked to a higher GBS risk, while mRNA vaccines (Pfizer-BioNTech, Moderna) and inactivated vaccines (Coronavac\/Sinovac) showed no increased risk.<\/p>\n\n\n\n<p>GBS, which causes progressive muscle weakness and paralysis, affects 1 to 4 people per 100,000 annually and has been associated with infections like Zika and influenza. The study\u2019s findings underscore the critical role of vaccination in mitigating severe health risks, as COVID-19 infection poses a greater threat than vaccination.<\/p>\n\n\n\n<p>Dr. Jeff Kwong, a senior author of the study, emphasized, \u201cReceiving an mRNA COVID-19 vaccine does not appear to increase your risk of GBS, but infection with the virus does. This highlights the importance of vaccination in protecting against serious complications.\u201d<\/p>\n\n\n\n<p>Dr. Sharifa Nasreen added, \u201cWhile certain vaccines may carry small risks, SARS-CoV-2 infection presents a much greater threat to neurological health.\u201d<\/p>\n\n\n\n<p>The study underscores the value of global collaboration in vaccine safety research and the need for continuous monitoring. It also reaffirms that vaccination remains a vital tool in reducing rare complications like GBS, alongside preventing severe COVID-19 outcomes. Future research will further explore these associations to guide public health strategies.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A multinational study analyzing data from over 230 million people has revealed that SARS-CoV-2 infection and certain adenoviral COVID-19 vaccines are associated with an increased risk of Guillain-Barr\u00e9 syndrome (GBS), a rare neurological disorder. The research, published in Vaccine, conducted across 20 global sites, found no such link with mRNA or inactivated vaccines, reinforcing the [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1565],"tags":[542,726,1566],"class_list":["post-5185","post","type-post","status-publish","format-standard","hentry","category-health-medicine","tag-covid-19","tag-health","tag-health-medicine"],"_links":{"self":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/5185","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5185"}],"version-history":[{"count":1,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/5185\/revisions"}],"predecessor-version":[{"id":5186,"href":"https:\/\/scientificworld.org\/index.php?rest_route=\/wp\/v2\/posts\/5185\/revisions\/5186"}],"wp:attachment":[{"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5185"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5185"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/scientificworld.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5185"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}